An Early-Stage Researcher (ESR) will be recruited as a PhD candidate to perform research in antibacterial drug discovery as part of the H2020-funded ITN project INNOTARGETS (https://cordis.europa.eu/project/id/956154).
Antimicrobial resistance is a growing medical challenge, hampering the effectiveness of existing drugs and threatening the lives of patients. Therefore, there is a pressing need for compounds that re-sensitise drug-resistant bacteria to existing antimicrobials. To address this problem, the EU-funded INNOTARGETS project will train early-stage researchers in the identification of novel metabolic drug targets in pathogenic bacteria. The project comes as a collaboration between academia and industry and will guide researchers to use innovative approaches to achieve their scientific goals. INNOTARGETS aims to provide ESRs with scientific and technical skills attractive to both industry and academia. ESRs will be equipped with complementary skills deemed important for research team leaders, will have an individual profile according to their own career dreams and will be capable of life-long self-directed learning. Each ESR will work closely together with 11 other ESRs in the INNOTARGETS network.
The selected candidate will be employed for three years at NAICONS Srl (Milan, Italy; www.naicons.com), where he/she will perform most of the research work aimed at identifying and characterizing novel antibacterial agents from microbial sources. The aim of the PhD project will be to develop and apply a screening platform designed to identify bioactive molecules which simultaneously block more than one pathway in bacteria. He/she is expected to perform part of the research work at secondment institutions and to register for a PhD programme at the University of Copenhagen, DK.
Eligibility criteria: Master degree (M.Sc. or equivalent graduation). Applicants must not have been awarded a PhD degree and must be in the first four years (full-time equivalent) of their research careers prior to the recruitment. They must not have resided or carried out their main activity (work, studies, etc.) in Italy for more than 12 months in the 3 years immediately prior to the recruitment. The communication and teaching language throughout INNOTARGETS is English, so proof of English proficiency is required.
Additional requirements: Degree in chemical or biological sciences with a strong background in chemistry, biochemistry and microbiology, with a strong interest in applied research and bioinformatics. Previous research experience with antibiotics, actinomycetes and/or natural products will be a plus.
Benefits: Salary and additional benefits are according to EU-standards for Marie Curie ESRs. Employment contract will be according to Italian labor laws.
Application: To apply, please send the following documents to: innotargets@naicons.com
EURAXESS Job Offer id: 573569
Application deadline: January 31, 2021
Planned start date: March to April 2021