Nov. 2023

NAICONS takes part in CLEAR project. The CLEAR (Cell Envelope Anti-bacterials) consortium is an EU-funded Marie Skłodowska-Curie European Training Network aimed at training 10 PhD students in antimicrobial resistance. Through a strong academic-industrial collaboration, the program focuses on developing novel antibacterial strategies targeting the bacterial cell envelope. The research aims to combat Gram-positive pathogens by addressing three levels of drug discovery. First, it seeks to identify novel drug targets by investigating bacterial resistance mechanisms. Second, it develops advanced screening methods using cell-based assays, virtual screening, and structural analysis of key envelope proteins to discover new leads. Third, it explores innovative therapeutic approaches, including drug repurposing, antimicrobial peptides with dual activity, and combination treatments involving antibiotics and bacteriophages.
For more info about project https://clear.ku.dk

Dec. 2022

NAICONS takes part in BREAKthrough, funded by the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie. BREAKthrough trains early stage researchers in Europe to to develop and apply novel tools to identify bioactive molecules and to address serious and global problems of antibiotic resistance. BREAKthrough will concentrate on the benefit of integrated multidisciplinary approaches to kill Gram-negative bacteria through existing antibiotics, by making their outer membrane permeable.
For more info about project https://breakthrough-project.eu/research/

Dec. 2022

NAICONS takes part in MAGic-MOLFUN, funded by the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie. MAGic-MOLFUN trains early stage researchers in Europe to to develop and apply novel tools to identify bioactive molecules and to address serious and global problems of antibiotic resistance. MAGic-MOLFUN will focus on the next generation of specialists through an educational program combining wet-lab and computational skills to integrate genome mining and metabolomics with cutting-edge pathway discovery and engineering approaches. For more info about project https://magic-molfun.dtu.dk/

Oct. 2021

NAICONS takes part in MARBLES, funded by the European Union’s Horizon 2020 research and innovation programme. The project, which is coordinated by Leiden University, NL, includes leading European laboratories involved in finding molecules produced by microorganisms. Naicons is proud to be the only Italian representative to be in the roster of Partners. MARBLES will use a novel and systematic approach to access and exploit marine microbial biodiversity for sustainable bioprospecting to discover microbial consortia and bioactive molecules for application in aqua, agriculture and in the clinic. For more info about project https://marblesproject.eu/

Gen. 2021

The Italian Ministry of Research has approved a 3-year, 2.95 M€ program (project code DM60066) for potentiating NAICONS technology platform for the discovery of new antibiotics. The project, which started on January 2020, involves developing new methods for discovery bioactive metabolites, smart screening programs and characterization and optimization of NAICONS proprietary antibacterial leads. The project is associated with an innovative program to train researchers in the discovery, characterization and development of new antibiotics.

Nov. 2020

NAICONS takes part in INNOTARGETS, funded by the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie. INNOTARGETS trains early stage researchers in Europe to address serious and global problems of antibiotic resistance. INNOTARGETS will focus on the identification of novel metabolic drug targets in pathogenic bacteria.
For more info about project https://innotargets.ku.dk

Nov. 2020

NAICONS takes part in PEST-BIN, funded by the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie. PEST-BIN trains early stage researchers in Europe to address serious and global problems of antibiotic resistance. PEST-BIN will focus on nano-engineering, antibiotic discovery and production, proteomics-based diagnostics and big data analysis using artificial intelligence. For more info about project https://www.sysbio.se/pest-bin_eu/

Nov. 2017

NAICONS takes part in CARTNET (Combating Antimicrobial Resistance – a training network), funded by the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie (No. 765147). CARTNET trains young researchers in Europe to address serious and global problems of antibiotic resistance. CARTNET will focus on alternative approaches to handle antibiotic resistance and treating resistant infections in both humans and animals. For more info about project https://cartnet.ku.dk/

Jan. 2017

NAICONS takes part in Rafts4Biotech (Synthetic bacterial lipid rafts to optimize industrial bioprocesses), funded by the European Commission under the Horizon 2020, H2020-NMBP-BIO-2016 (No. 720776) For more info about project http://www.rafts4biotech.eu/

Jan. 2017

NAICONS takes part in TOPCAPI (Thoroughly Optimised Production Chassis for Advanced Pharmaceutical Ingredients), funded by the European Commission under the Horizon 2020, H2020-NMBP-BIO-2016 (no. 720793). For more info about project http://topcapi.eu/

Jan. 2017

NAICONS takes part in Train2Target, an European Training Network funded by the European Commission under the Horizon 2020 Marie Skłodowska-Curie Action (no. 721484). The project, which started on January 2017 and will last until December 2020, involves 11 Beneficiaries from 8 different countries and is dedicated to the scientific and professional training of 15 Early Stage Researchers (PhDs). The aim of the Train2Target programme is to deliver leads for a new generation of innovative antibacterials to treat infections by multi-drug resistant pathogens. For more info about project https://www.train2target.eu/

Apr. 2015

NAICONS, in collaboration with KtedoGen (KG), takes part in NoMoreFilm project (Novel marine biomolecules against biofilm. Application to medical devices) funded by the European Commission under the Horizon 2020 (UE-15-NOMORFILM-634588). For more info about project http://www.nomorfilm.eu/

COMPLETED:

• Regione Lombardia (PROGRAMMA OPERATIVO REGIONALE 2014-2020) for “CLARISSIMO” – Studio e messa a punto di nuovi processi biocatalizzati per la modifica e produzione di antibiotici. ID Progetto: 138464
• NIH-NIAID for “Therapeutics for Drug-resistant Bacteria: Pseudouridimycins”. Project No. 5R01AI104660-02
• MIUR- SPRING (Italian Cluster of Green Chemistry) for “REBIOCHEM”
• Biochemicals da biomasse: integrazioni di bio-conversioni per la produzione e l’applicazione di biochemicals da biomasse di II generazione da fonti rinnovabili. ID Progetto: CTN01_00063_49393
• Eureka-EC (Eurostars programme) for “NOSTRADAMUS” – NOvel STRAtegy for Drug discovery by A Microbiome-based approach: Use of PathoGut™ for predictive antibiotic Screening- Application E!8404
• EC-FP7 (FP7-PEOPLE-2011-ITN) for “TRAIN-ASAP”- Training and Research AImed at Novel Antibacterial Solutions in Animals and People. Grant No. 289285
• EC-FP7 (FP7-KBBE-2009-3) for “LAPTOP” – Lantibiotic production, Technology, optimization and improved process). Grant No. 245066
• Regione Lombardia (RL-MIUR 2011) for “Nuovi antibiotici mediante rational design”. ID Progetto 30190679
• Regione Lombardia (Programma Operativo regionale 2007-2013) for “NAI-Acne” ID Progetto: 13810096